M. en C. LILIA LEYVA CARRILLO
M.C. Lilia Leyva Carrillo

Profesora Investigadora Asociada A

Líneas de investigación: Metabolismo energético central, alteraciones en expresión y actividad enzimática en respuesta a hipoxia; Sistema antioxidante y respuestas a estresores ambientales; Efectos de contaminantes tóxicos en organismos acuáticos

Metabolismo energético Sistemas antioxidantes Estrés oxidativo Hipoxia Contaminantes tóxicos

Google AcadémicoResearchGate

Coordinación

Tecnología de Alimentos de Origen Animal

Teléfono

(+52) 662 289 2400, ext. 614

Correo electrónico

liley@ciad.mx

  • Químico Biólogo por la Universidad de Sonora (1995)
  • Maestra en Ciencias por el Centro de Investigación en Alimentación y Desarrollo, A. C., Hermosillo, Son. (2001)
  • Respuestas metabólicas y de sistemas antioxidantes ante el estrés ambiental y por contaminantes en crustáceos marinos

Publicaciones seleccionadas, últimos 6 años 2019-2024

  1. Camacho Jiménez L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S., Yepiz Plascencia G.M. 2024. Peroxiredoxin 6 (Prx6) of Penaeus vannamei and effect of phenanthrene on Prx6 and glutathione peroxidase 4 expression, glutathione-dependent peroxidase activity and lipid peroxidation. Comparative Biochemistry and Physiology, Part C 286. 110014. https://doi.org/10.1016/j.cbpc.2024.110014
  2. Cruz Moreno D., Hernández Aguirre L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S.,Contreras Vergara C.A.,Hernández López J., Yepiz Plascencia G.M. 2024. Changes of glycolysis and gluconeogenesis key enzymes in the muscle of the shrimp Penaeus vannamei in response to hypoxia and reoxygenation. Journal of Experimental Marine Biology and Ecology 580.152052. https://doi.org/10.1016/j.jembe.2024.152052
  3. Camacho Jiménez L., Leyva Carrillo L., Gómez Jiménez S., Yépiz Plascencia G.M. 2024. Naphthalene and phenanthrene affect differentially two glutathione S-transferases (GSTs) expression, GST activity, and glutathione content in white shrimp P. vannamei. Aquatic Toxicology 273. 107005
  4. Flores Sauceda M., Leyva Carrillo L., Camacho Jiménez L., Gómez Jiménez S., Peregrino Uriarte A.B., Yepiz Plascencia G.M. 2024. Two hexokinases of the shrimp Penaeus (Litopenaeus) vannamei are differentially expressed during oxygen limited conditions. Comparative Biochemistry and Physiology, Part A 293. 111637. https://doi.org/10.1016/j.cbpa.2024.111637.
  5. González Ruiz N., Leyva Carrillo L.,Coronado Molina D.,Hernández Lopez J., Yepiz Plascencia G.M. 2023. Antioxidant stress response to fluctuations of dissolved oxygen and temperature in a semi-intensive aquaculture shrimp farm during high summer temperature. Invertebrate Survival Journal. 20: 65-78. https://www.isj.unimore.it/index.php/ISJ/article/view/803/505.
  6. Romero-Reyes A., Hernandez-Leon S.G., Leyva-Carrillo L., Yepiz-Plascencia G.M., Reynolds, M.P., Paul, M.J., Heuer, S. and Valenzuela-Soto, E.M. 2023. An efficient triose phosphate synthesis and distribution in wheat provides tolerance to higher field temperatures. Biochemical Journal 480: 1365–1377. https://doi.org/10.1042/BCJ20230117
  7. Estrada-Cardenas P., Peregrino-Uriarte A.B., Gómez-Jiménez S., Valenzuela-Soto E.M., Leyva Carrillo L., Yepiz Plascencia G. 2023. Responses and modulation of the white shrimp Litopenaeus vannamei glutathione peroxidases 2 and 4 during hypoxia, reoxygenation and GPx4 knock-down. Biochimie214:157-164. https://doi.org/10.1016/j.biochi.2023.07.006
  8. Camacho Jiménez L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S., Thies A., Tresguerres M., Yepiz Plascencia G. 2023. Effects of severe hypoxia and glyceraldehyde-3- phosphate dehydrogenase (GAPDH) knock- down on its gene expression, activity, subcellular localization, and apoptosis in gills of the shrimp Penaeus vannamei. Marine and Freshwater Behaviour and Physiology. 56(3–4):91–110 https://doi.org/10.1080/10236244.2023.2216346
  9. Cruz-Moreno P., Valenzuela-Soto E, Peregrino-Uriarte A.B., Leyva-Carrillo L., Soñanez-Organis J.G., Yepiz-Plascencia G. 2023. The pyruvate kinase of the whiteleg shrimp Litopenaeus vannamei: Gene structure and responses to short term hypoxia. Comp Biochem Physiol A Mol Integr Physiol. 283: 111468, https://doi.org/10.1016/j.cbpa.2023.111468
  10. Hernández-Aguirre L.E., Peregrino-Uriarte A-B., Duarte Gutiérrez J.L., Leyva-Carrillo L., Ezquerra-Brauer J.M., Valenzuela-Soto E.M., Yepiz-Plascencia G. 2023. Shrimp Glucose-6-Phosphatase 2 (G6Pase 2): a second isoform of G6Pase in the Pacific white shrimp and regulation of G6Pase 1 and 2 isoforms via HIF-1 during hypoxia and reoxygenation in juveniles. J Bioenergetics and Biomembranes https://doi.org/10.1007/s10863-023-09960-z
  11. González-Ruiz R., Leyva-Carrillo L., Peregrino-Uriarte A.B., Yepiz-Plascencia G. 2022. The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei). Cell Stress Chaperones. doi: 10.1007/s12192-022-01265-1.
  12. Flores-Sauceda M., Camacho-Jiménez L., Peregrino-Uriarte A.B., Leyva-Carrillo L., Arvizu-Flores A., Yepiz-Plascencia G. 2022. The bifunctional 6-phosphofructokinase-2/frustose-2,6-bisphoshatase from the shrimp Litopenaus vannamei: Molecular characterization and down-regulation of expression in response to severe hypoxia. Comp Biochem Physiol, Part A. 263: 111095 https://doi.org/10.1016/j.cbpa.2021.111095
  13. Nuñez-Hernández D., Camacho-Jiménez L., Leyva-Carrillo L., Peregrino-Uriarte A.B., Valenzuela-Soto E.M., Gómez-Jiménez S., Gonzalez-Rios H., Yepiz- Plascencia G. 2021. Expression of p53 isoforms in response to two levels of hypoxia and effects of p53 knock-down in glyceraldehyde-3-phpsphate dehydrogenase in the white shrimp Litopenaeus vannamei. Aq Res. 00:1-11. DOI: 10.1111/are.15083
  14. Estrada-Cárdenas P., Cruz-Moreno D., González-Ruiz R., Peregrino-Uriarte A., Leyva-Carrillo L., Camacho-Jiménez L., Quintero-Reyes I., Yepiz-Plascencia G. 2021. Combined hypoxia and high temperature affect differentially the response of antioxidant enzymes, glutathione and hydrogen peroxide in the White shrimp Litopenaeus vannamei. Comp Biochem Physiol, Part A. 254: 110909. doi.org/10.1016/j.cbpa.2021.110909
  15. Duarte-Gutierrez J., Leyva-Carrillo L., Martinez-Tellez M.A., Mendez-Estrada R. O.; Felix-Portillo M., Yepiz-Plascencia G. 2020. Cloning, expression, purification and biochemical characterization of recombinant metallothionein from the white shrimp Litopenaeus vannamei. Prot Exp Pur. 166: 105511
  16. Camacho-Jiménez L., Leyva-Carrillo L. Peregrino-Uriarte A.B., Duarte-Gutierrez J., Tresguerres M., Yepiz-Plascencia G. 2019. Regulation of glyceraldehyde-3-phosphate dehydrogenase by hypoxia inducible factor 1 in the white shrimp Litopenaeus vannamei during hypoxia and reoxygenation. Comp Biochem Physiol A-Mol Int Physiol. 235:56-65.
  17. Leyva-Carrillo L., Hernandez-Palomares M., Valenzuela-Soto E.M., Figueroa-Soto C., Yepiz-Plascencia G. 2019. Purification and partial biochemical characterization of recombinant lactate dehydrogenase 1 (LDH-1) of the white shrimp Litopenaeus vannamei Prot Exp Pur. 164:105461 https://doi.org/10.1016/j.pep.2019.105461
  • Expresión y epigenética de los sistemas antioxidantes y de biotransformación de xenobióticos en camarón ante dos estresores: hipoxia y contaminación por hidrocarburos aromáticos policíclicos, CONAHCYT CBF2023-2024-595
Formación profesional
  • Químico Biólogo por la Universidad de Sonora (1995)
  • Maestra en Ciencias por el Centro de Investigación en Alimentación y Desarrollo, A. C., Hermosillo, Son. (2001)
Áreas de interés
  • Respuestas metabólicas y de sistemas antioxidantes ante el estrés ambiental y por contaminantes en crustáceos marinos
Publicaciones seleccionadas

Publicaciones seleccionadas, últimos 6 años 2019-2024

  1. Camacho Jiménez L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S., Yepiz Plascencia G.M. 2024. Peroxiredoxin 6 (Prx6) of Penaeus vannamei and effect of phenanthrene on Prx6 and glutathione peroxidase 4 expression, glutathione-dependent peroxidase activity and lipid peroxidation. Comparative Biochemistry and Physiology, Part C 286. 110014. https://doi.org/10.1016/j.cbpc.2024.110014
  2. Cruz Moreno D., Hernández Aguirre L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S.,Contreras Vergara C.A.,Hernández López J., Yepiz Plascencia G.M. 2024. Changes of glycolysis and gluconeogenesis key enzymes in the muscle of the shrimp Penaeus vannamei in response to hypoxia and reoxygenation. Journal of Experimental Marine Biology and Ecology 580.152052. https://doi.org/10.1016/j.jembe.2024.152052
  3. Camacho Jiménez L., Leyva Carrillo L., Gómez Jiménez S., Yépiz Plascencia G.M. 2024. Naphthalene and phenanthrene affect differentially two glutathione S-transferases (GSTs) expression, GST activity, and glutathione content in white shrimp P. vannamei. Aquatic Toxicology 273. 107005
  4. Flores Sauceda M., Leyva Carrillo L., Camacho Jiménez L., Gómez Jiménez S., Peregrino Uriarte A.B., Yepiz Plascencia G.M. 2024. Two hexokinases of the shrimp Penaeus (Litopenaeus) vannamei are differentially expressed during oxygen limited conditions. Comparative Biochemistry and Physiology, Part A 293. 111637. https://doi.org/10.1016/j.cbpa.2024.111637.
  5. González Ruiz N., Leyva Carrillo L.,Coronado Molina D.,Hernández Lopez J., Yepiz Plascencia G.M. 2023. Antioxidant stress response to fluctuations of dissolved oxygen and temperature in a semi-intensive aquaculture shrimp farm during high summer temperature. Invertebrate Survival Journal. 20: 65-78. https://www.isj.unimore.it/index.php/ISJ/article/view/803/505.
  6. Romero-Reyes A., Hernandez-Leon S.G., Leyva-Carrillo L., Yepiz-Plascencia G.M., Reynolds, M.P., Paul, M.J., Heuer, S. and Valenzuela-Soto, E.M. 2023. An efficient triose phosphate synthesis and distribution in wheat provides tolerance to higher field temperatures. Biochemical Journal 480: 1365–1377. https://doi.org/10.1042/BCJ20230117
  7. Estrada-Cardenas P., Peregrino-Uriarte A.B., Gómez-Jiménez S., Valenzuela-Soto E.M., Leyva Carrillo L., Yepiz Plascencia G. 2023. Responses and modulation of the white shrimp Litopenaeus vannamei glutathione peroxidases 2 and 4 during hypoxia, reoxygenation and GPx4 knock-down. Biochimie214:157-164. https://doi.org/10.1016/j.biochi.2023.07.006
  8. Camacho Jiménez L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S., Thies A., Tresguerres M., Yepiz Plascencia G. 2023. Effects of severe hypoxia and glyceraldehyde-3- phosphate dehydrogenase (GAPDH) knock- down on its gene expression, activity, subcellular localization, and apoptosis in gills of the shrimp Penaeus vannamei. Marine and Freshwater Behaviour and Physiology. 56(3–4):91–110 https://doi.org/10.1080/10236244.2023.2216346
  9. Cruz-Moreno P., Valenzuela-Soto E, Peregrino-Uriarte A.B., Leyva-Carrillo L., Soñanez-Organis J.G., Yepiz-Plascencia G. 2023. The pyruvate kinase of the whiteleg shrimp Litopenaeus vannamei: Gene structure and responses to short term hypoxia. Comp Biochem Physiol A Mol Integr Physiol. 283: 111468, https://doi.org/10.1016/j.cbpa.2023.111468
  10. Hernández-Aguirre L.E., Peregrino-Uriarte A-B., Duarte Gutiérrez J.L., Leyva-Carrillo L., Ezquerra-Brauer J.M., Valenzuela-Soto E.M., Yepiz-Plascencia G. 2023. Shrimp Glucose-6-Phosphatase 2 (G6Pase 2): a second isoform of G6Pase in the Pacific white shrimp and regulation of G6Pase 1 and 2 isoforms via HIF-1 during hypoxia and reoxygenation in juveniles. J Bioenergetics and Biomembranes https://doi.org/10.1007/s10863-023-09960-z
  11. González-Ruiz R., Leyva-Carrillo L., Peregrino-Uriarte A.B., Yepiz-Plascencia G. 2022. The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei). Cell Stress Chaperones. doi: 10.1007/s12192-022-01265-1.
  12. Flores-Sauceda M., Camacho-Jiménez L., Peregrino-Uriarte A.B., Leyva-Carrillo L., Arvizu-Flores A., Yepiz-Plascencia G. 2022. The bifunctional 6-phosphofructokinase-2/frustose-2,6-bisphoshatase from the shrimp Litopenaus vannamei: Molecular characterization and down-regulation of expression in response to severe hypoxia. Comp Biochem Physiol, Part A. 263: 111095 https://doi.org/10.1016/j.cbpa.2021.111095
  13. Nuñez-Hernández D., Camacho-Jiménez L., Leyva-Carrillo L., Peregrino-Uriarte A.B., Valenzuela-Soto E.M., Gómez-Jiménez S., Gonzalez-Rios H., Yepiz- Plascencia G. 2021. Expression of p53 isoforms in response to two levels of hypoxia and effects of p53 knock-down in glyceraldehyde-3-phpsphate dehydrogenase in the white shrimp Litopenaeus vannamei. Aq Res. 00:1-11. DOI: 10.1111/are.15083
  14. Estrada-Cárdenas P., Cruz-Moreno D., González-Ruiz R., Peregrino-Uriarte A., Leyva-Carrillo L., Camacho-Jiménez L., Quintero-Reyes I., Yepiz-Plascencia G. 2021. Combined hypoxia and high temperature affect differentially the response of antioxidant enzymes, glutathione and hydrogen peroxide in the White shrimp Litopenaeus vannamei. Comp Biochem Physiol, Part A. 254: 110909. doi.org/10.1016/j.cbpa.2021.110909
  15. Duarte-Gutierrez J., Leyva-Carrillo L., Martinez-Tellez M.A., Mendez-Estrada R. O.; Felix-Portillo M., Yepiz-Plascencia G. 2020. Cloning, expression, purification and biochemical characterization of recombinant metallothionein from the white shrimp Litopenaeus vannamei. Prot Exp Pur. 166: 105511
  16. Camacho-Jiménez L., Leyva-Carrillo L. Peregrino-Uriarte A.B., Duarte-Gutierrez J., Tresguerres M., Yepiz-Plascencia G. 2019. Regulation of glyceraldehyde-3-phosphate dehydrogenase by hypoxia inducible factor 1 in the white shrimp Litopenaeus vannamei during hypoxia and reoxygenation. Comp Biochem Physiol A-Mol Int Physiol. 235:56-65.
  17. Leyva-Carrillo L., Hernandez-Palomares M., Valenzuela-Soto E.M., Figueroa-Soto C., Yepiz-Plascencia G. 2019. Purification and partial biochemical characterization of recombinant lactate dehydrogenase 1 (LDH-1) of the white shrimp Litopenaeus vannamei Prot Exp Pur. 164:105461 https://doi.org/10.1016/j.pep.2019.105461
Proyectos vigentes
  • Expresión y epigenética de los sistemas antioxidantes y de biotransformación de xenobióticos en camarón ante dos estresores: hipoxia y contaminación por hidrocarburos aromáticos policíclicos, CONAHCYT CBF2023-2024-595
Grupos de investigación
Laboratorios
Líneas de Generación y Aplicación del Conocimiento
  • Biotecnología de Organismos Marinos
  • Biología Molecular
  • Biotecnología de Organismos Acuáticos